WebApp MDRA

is a web application for performing dose-response analysis of multiple experiments.

- Application of the four-parameter log-logistic model to fit dose-response data.

- Visualization of dose-response data containing multiple experiments by applying DORES (dose-response screening) plot.

For details about DORES plot, see: Jiang, Xiaoqi, and Annette Kopp-Schneider. Statistical strategies for averaging EC50 from multiple dose-response experiments. Archives of Toxicology. (2014)

- Application of the meta-analysis approach to performing averaging analysis of dose-response data from multiple experiments.

For details, see: Jiang, Xiaoqi, and Annette Kopp-Schneider. Summarizing EC50 estimates from multiple dose-response experiments: A comparison of a meta-analysis strategy to a mixed-effects model approach. Biometrical Journal. 56(3): 493-512 (2014).

The browsers Chrome and Firefox are recommended for users!

- Download User Guide

- Download Example Data

For help, please use the contact form or email kopp (at) dkfz-heidelberg.de